Diabetes in the young but not needing insulin - what type is it?

health communication what it is and what is not

P-value: What is and what is not

The misinterpretation and misuse of p-value have been increasing for decades. In March 2016, the American Statistical Association released a statement to warn about the use and interpretation of p-value. In this study, we provided a definition and discussion of p-value and emphasized the importance of its accurate interpretation.    

Understanding Heritability: What it is and What it is Not

Copy Abstract: Commentators generally found our exposition of the concept of heritability helpful for psychologists, suggesting that we largely accomplished our primary goal. Many provided supplemental and helpful perspectives on concepts we addressed. A few of the comments indicated that we may not have been completely successful in making clear our secondary goal, which was to outline how her...

Gene therapy : what it is , what it is not and what it will be

Gene therapy is the therapeutic procedure based on the introduction of healthy genes using recombinant DNA techniques. the first successful clinical trial of this technique was published in 1990. Despite the occurrence of adverse effects in certain clinical trials, some of them serious, both laboratories and companies are continuously developing novel materials and establishing both safer and m...

Islet Amyloid Polypeptide is not a Target Antigen for CD8+ T-Cells in Type 2 Diabetes

Background: Type 2 diabetes (T2D) is a chronic metabolic disorder in which beta-cells are destroyed. The islet amyloid polypeptide (IAPP) produced by beta-cells has been reported to influence beta-cell destruction. Objective: To evaluate if IAPP can act as an autoantigen and therefore, to see if CD8 + T-cells specific for this protein might be present in T2D patients. Methods: Peripheral blood ...